On a Distribution Function Arising in Computational Biology

نویسندگان

  • Craig A. Tracy
  • Harold Widom
چکیده

where Rk,r is the number of permutations of the integers {1, . . . , k} that contain an increasing subsequence of length at least r. Let Xy denote a positive integer valued random variable such that Prob (Xy ≥ r) = F (r; y). If R k,r denotes the complement of Rk,r, i.e. the number of permutations σ ∈ Sk all of whose increasing subsequences have length strictly less than r, then clearly R k,r = # {σ ∈ Sk : lk(σ) < r} = # {σ ∈ Sk : lk(σ) ≤ r − 1} := fk,r−1 where lk(σ) is the length of the longest increasing subsequence in σ ∈ Sk. Remarks 1. F (r; y) is a distribution function in r with parameter y. 2. Dropping the requirement of consistent ordering has the effect of replacing Rk,r by k! in (1). Thus the segments are Poisson distributed with parameter y. By convention, f0,r := 1 for all r and we note that fk,r = k! if k ≤ r. It is also convenient to introduce the parameter t ≥ 0, y = t. If we define Dr(t) = ∞

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Distribution Function Arising in Computational Biology

Karlin and Altschul in their statistical analysis for multiple highscoring segments in molecular sequences introduced a distribution function which gives the probability there are at least r distinct and consistently ordered segment pairs all with score at least x. For long sequences this distribution can be expressed in terms of the distribution of the length of the longest increasing subseque...

متن کامل

A Bayesian approach for image denoising in MRI

Magnetic Resonance Imaging (MRI) is a notable medical imaging technique that is based on Nuclear Magnetic Resonance (NMR). MRI is a safe imaging method with high contrast between soft tissues, which made it the most popular imaging technique in clinical applications. MR Imagechr('39')s visual quality plays a vital role in medical diagnostics that can be severely corrupted by existing noise duri...

متن کامل

استفاده از رگولاریزاسیون خطی برای پیش‌بینی توابع توزیع دارای چند پیک در جاذبهای ناهمگن

In the present article an energy distribution function of heterogeneous solid was estimated. Energy distribution function is an important characterization for heterogeneous adsorbent. An overall adsorption quantity for a heterogeneous solid is usually expressed by a first kind of Fredholm equation, which contains unknown distribution function and local adsorption isotherm as a kernel. The calcu...

متن کامل

Experimental study and application of computational fluid dynamics on the prediction of air velocity and temperature in a ventilated chamber

The shape of the air flow in the interior is heavily influenced by the air distribution system and the way air enters and exits. By numerically simulating flow by computational fluid dynamics, one can determine the flow pattern and temperature distribution and, with the help of the results, provide an optimal design of the air conditioning system. In this study, a chamber was first constructed ...

متن کامل

Using the Modified Shuffled Frog Leaping Algorithm for Optimal Sizing and location of Distributed Generation Resources for Reliability Improvement

Restructuring the recent developments in the power system and problems arising from construction as well as the maintenance of large power plants lead to increase in using the Distributed Generation (DG) resources. DG units due to its specifications, technology and location network connectivity can improve system and load point reliability indices. In this paper, the allocation and sizing of di...

متن کامل

Structural insights into the effects of charge-reversal substitutions at the surface of horseradish peroxidase

Horseradish peroxidase (HRP), has gained significant interests in biotechnology, especially in biosensor field and diagnostic test kits. Hence, its solvent-exposed lysine residues 174, 232, and 241 have been frequently modified with the aim of improving its stability and catalytic efficiency. In this computational study, we investigated the effects of Lys-to-Glu substitutions on HRP structure t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000